The new 3 Gigabit/second eSATA cards contain a rather large Marvell chip with the string "88SX6081" on it. Previous generation eSATA cards had a Marvell chip labeled "88SX5081". Additionally, you can check your Macintosh System Profile. When you select the installed eSATA card, the Device ID will show either "0x6081" or "0x5081".
Yes, this is a great way to expand capacity and performance. If two or more Tempo-X, X4+4, X8, X4i, X4P, E4i, or E4P cards are installed to the same machine they must all have the same firmware version to avoid conflicts.