Spread Spectrum Clocking is a way to lower electromagnetic interference or EMI. This is important for storage solutions that are required to pass FCC and other agency certifications. All current Serial ATA disk drives implement SSC (some allow you to turn this feature on/off). However, some older SATA drives do not implement SSC. All Sonnet Serial ATA host adapter cards support SSC but will also work with disk drives that do not.
Macintosh bootable volumes are supported on the internal 2-port PCI card (part number TSATA) but are not supported on any of the other SATA cards at this time.
Using a Drobo S with a Macintosh and Sonnet Tempo SATA E2P, Tempo SATA ExpressCard/34, or Tempo SATA Edge ExpressCard/34. you may get a device removal error after waking up from sleep. The Drobo S will automatically reconnect. System caches are flushed before sleep, so there is not data loss.