Hot-swap functionality enables you to connect and disconnect drives without having to power down your computer. This does not mean you can simply pull out a drive at any time; you must put away ("eject", "unmount", "dismount") the drive volume. For Mac OS X users, simply drag the drive icon associated with the drive(s) you wish to remove to the eject icon on the dock; Windows users using a Tempo SATA ExpressCard/34 may left-click on the eject icon in the taskbar for the drive they wish to eject. Only after the drives are ejected (unmounted) is it safe for you to disconnect the drives or cables. If you do not follow this procedure, data on your drives may become corrupted.
A Lion install removes the driver for the Tempo SATA E2P, Tempo SATA ExpressCard/34, and Tempo SATA edge ExpressCard/34. Just reinstall the driver and the card will work again.