Sonnet has tested the following cards with the Drobo S:
Tempo SATA E2P..............................compatible
Tempo SATA E4P..............................not compatible
Tempo SATA ExpressCard/34...........compatible
Tempo SATA Edge ExpressCard/34...compatible
Tempo SATA Pro ExpressCard/34.....not compatible
Tempo SATA X4P..............................not compatible
Qio eSATA ports...............................not compatible
Yes, but you must hot plug the Qio's interface card into the ExpressCard/34 slot of the 17" Thunderbolt MacBook Pro. The Qio will not be recognized in the 17" Thunderbolt MacBook Pro if you boot or restart with the Qio plugged into the ExpressCard/34 slot. See FAQ 632 for more infomation about compatibility connecting Qio via Thunderbolt.