Sonnet has tested the following cards with the Drobo S:
Tempo SATA E2P..............................compatible
Tempo SATA E4P..............................not compatible
Tempo SATA ExpressCard/34...........compatible
Tempo SATA Edge ExpressCard/34...compatible
Tempo SATA Pro ExpressCard/34.....not compatible
Tempo SATA X4P..............................not compatible
Qio eSATA ports...............................not compatible
The first time you boot with the Qio connected, the screen will stay blue for up to 6 minutes while the Mac is configuring the Qio slot space. Please be patient. Subsequent boots should be normal. Note that you must install the Qio software before connecting the Qio.
Sonnet measured read performance for three manufacturers' 600X (90MB/sec) CF cards in the Qio, connected to a MacBook Pro:
Lexar Professional 600X...86MB/sec
Transcend 600X...............71MB/sec
SanDisk Extreme Pro........61MB/sec