Often, yes. Sometimes, not. Some other manufacturers' drivers may incorrectly assume a Sonnet card is their SATA card which may cause havoc. The symptoms include significantly slower performance, driver not loading, or both drivers loading and causing and kernel panics as they both try to access the same card. Sonnet recommends removing other manufacturer's card(s) and driver(s) if a problem of this type occurs.
Using a Drobo S with a Macintosh and Sonnet Tempo SATA E2P, Tempo SATA ExpressCard/34, or Tempo SATA Edge ExpressCard/34. you may get a device removal error after waking up from sleep. The Drobo S will automatically reconnect. System caches are flushed before sleep, so there is not data loss.