Using a Drobo S with a Macintosh and Sonnet Tempo SATA E2P, Tempo SATA ExpressCard/34, or Tempo SATA Edge ExpressCard/34. you may get a device removal error after waking up from sleep. The Drobo S will automatically reconnect. System caches are flushed before sleep, so there is not data loss.
Unfortunately, not. The driver was written by the 3Gb SATA controller chip maker, Silicon Image, and they no longer maintain the macOS driver for this chip.